In addition to leveraging their AS/CAN/NAAR-funded studies to earn larger autism research grants from the National Institutes of Health and other sources, researchers funded by AS/CAN/NAAR have experienced significant success publishing their studies in numerous scientific journals and books. These publications play a key role in enhancing the scientific community’s understanding of autism spectrum disorders and elevating the caliber of the science.
Autism Speaks is proud to present this partial list of articles that have resulted from AS/CAN/NAAR-funded research from 1996 to 2007. The funded researchers are listed in bold.
Baranek GT, Barnett CR, Adams EM, Wolcott NA, Watson LR, and Crais ER. (2005) Object play in infants with autism: methodological issues in retrospective video analysis. Am J Occup Ther, 59(1):20-30.
Baranek GT, Danko CD, Skinner ML, Hatton DB, Roberts JE, and Mirrett PL. (2005) Analysis of Sensory-Motor Features in Infants with Fragile X Syndrome at 9-12 Months of Age. J Autism Dev Disord, 35(5):645-56.
Baron-Cohen S, Knickmeyer RC and Belmonte M. (2005) Sex differences in the brain: implications for explaining autism. Science,310: 819-822.
Baron-Cohen S, Belmonte MK. (2005) Autism: a window onto the development of the social and the analytic brain. Annu Rev Neurosci, 28:109-26.
Bartlett CW, Gharani N, Millonig JH, Brzustowicz LM. (2005) Three autism candidate genes: a synthesis of human genetic analysis with other disciplines. International Journal of Developmental Neuroscience,Vol. 2:21-234.
Belmonte MK. (2005) Abnormal visual motion processing as a neural endophenotype of autism. Cahiers de Psychologie Cognitive / Current Psychology of Cognition, 23 (1-2): 65-74.
Benayed R, Gharani N, Rossman I, Mancuso V, Lazar G, Kamdar S, Bruse SE, Tischfield S, Smoth BJ, Zimmerman, RA, DiCicco-Bloom E, Brzustowicz L and Millonig JH. (2005) Support for the homeobox transcription factor gene ENGRAILED2 as an Autism Spectrum Disorder susceptibility locus. American Journal of Human Genetics,77(5):851-68.
Blatt GJ. (2005) GABAergic cerebellar system in autism: a neuropathological and developmental perspective. International Review of Neurobiology, 71:167-178.
Boucard AA, Chubykin AA, Comoletti D, Taylor P, and Sudhof TC. (2005) A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron, 48(2):229-36.
Carter CS. (2005) Biological perspectivies on social attachment and bonding. In “Attachment and Bonding: A New Synthesis.”Carter, et al, eds. (MIT Press). 85-100.
Casanova MF, de Zeeuw L, Switala A, Kreczmanski P, Korr H, Ulfig N, Heinsen H, Steinbusch HWM, Schmitz C. (2005) Lamination abnormalities in the neocortex of patients with schizophrenia. Psychological Research, 133(1):1-12.
Charman T, Taylor E, Drew A, Cockerill H, Brown JA, and Baird G. (2005) Outcome at 7 years of children diagnosed with autism at age 2: predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. J Child Psychol Psychiatry, 46(5):500-13.
Chubykin A, Xinran L, Comoletti D, Tsignelny I, Taylor P, and Südhof T. (2005) Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. JBC Press, 280: 22365–22374.
Chubykin A, Liu X, Comoletti D, Tsigelny I, Taylor P, and Südhof T. (2005) Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism , J Biol Chem.Mar 29.
D’Amelio M, Ricci I, Sacco R, Liu X, D’Agruma L, Muscarella LA, Guarnieri V, Militerni R, Bravaccio C, Elia M, Schneider C, Melmed R, Trillo S, Pascucci T, Puglisi-Allegra S, Reichelt KL, Macciardi F, Holden JJ, and Persico AM. (2005) Paraoxonase gene variants are associated with autism in North America, but not in Italy: possible regional specificity in gene-environment interactions. Mol Psychiatry, 10(11):1006-16.
Dapretto M, Lee SS, and Caplan R. (2005) A functional magnetic resonance imaging study of discourse coherence in typically developing children. Neuroreport, 16(15):1661-5.
Deaner RO, Khera AV, and Platt ML. (2005) Monkeys pay per view: adaptive valuation of social images by rhesus macaques. Curr Biol, 15(6):543-8.
Delorme R, Betancur C, Wagner M, Krebs MO, Gorwood P, Pearl P, Nygren G, Durand CM, Buhtz F, Pickering P, Melke J, Ruhrmann S, Anckarsater H, Chabane N, Kipman A, Reck C, Millet B, Roy I, Mouren-Simeoni MC, Maier W, Rastam M, Gillberg C, Leboyer M, and Bourgeron T. (2005) Support for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorder. Mol Psychiatry, 10(12):1059-61.
Depew MJ, Simpson CA, Morasso M, and Rubenstein JL. (2005) Reassessing the Dlx code: the genetic regulation of branchial arch skeletal pattern and development. J Anat, 207(5):501-61.
Dziobek I, Rogers K, Fleck S, Hassenstab J, Gold S, Wolf OT, and Convit A. (2005) In search of master mindreaders: Are psychics superior in reading the language of the eyes? Brain and Cognition,58(2):240-44.
Ferland RJ, Li X, Buhlmann JE, Bu X, Walsh CA, and Lim B. (2005) Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res., 1054(1):9-21.
Flagg EJ, Cardy JEO, Roberts W, and Roberts TPL. (2005) Language lateralization development in children with autism: Insights from the late field magnetoencephalogram. Neuroscience Letters,386: 82-87.
Greenspan S and Shanker S. (2005) Differences in affect cuing: A window for the identification of risk patterns for autism spectrum disorders in the first year of life. The Journal of Developmental and Learning Disorders, 6:23-30.
Hamilton SP, Woo JM, Carlson EJ, Ghanem N, Ekker M, and Rubenstein JL. (2005) Analysis of four DLX homeobox genes in autistic probands. BMC Genet, 6:52.
Hashimoto T, Bergen S, Nguyen QL, Xu B, Monteggia L, Pierri J, Sun Z, Sampson A, and Lewis D. (2005) Relationship of Brain-Derived Neurotrophic Factor and Its Receptor TrkB to Altered Inhibitory Prefrontal Circuitry in Schizophrenia. Journal of Neuroscience, 25:372-383.
Hayes GR, Truong KN, Abowd GD, and Pering T. (2005) Exerience Buffers: A socially Appropriate, Selective Archiving Tool for Evidence-Based Care. In Proceedings of CHI ’05, April 2-7, 2005, Portland, OR.
Herbert MR. (2005) Autism: a brain disorder or a disorder affecting the brain? Clinical Neuropsychiatry, 2:354:379.
Herbert MR. (2005) Large brains in autism: the challenge of pervasive abnormality. Neuroscientist, 11(5):417-40.
Herbert MR and Ziegler DA. (2005) Volumetric neuroimaging and low-dose early-life exposures: loose coupling of pathogenesis-brain-behavior links. Neurotoxicology, 26(4):565-72.
Herbert MR, Ziegler DA, Deutsch CK, O’Brien LM, Kennedy DN, Filipek PA, Bakardjiev AI, Hodgson J, Takeoka M, Makris N, and Caviness VS. (2005) Brain asymmetries in autism and developmental language disorder: a nested whole-brain analysis. Brain, 128(Pt 1):213-26.
Hollander E, Phillips A, Chaplin W, Zagursky K, Novotny S, Wasserman S, and Iyengar R. (2005) A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology, 30(3):582-9.
Holmboe K and Johnson MH. (2005) Educating executive attention. Proceedings of the National Academy of Sciences of the USA, 102(41):14479-14480.
Kientz JA, Boring S, Abowd GD, Hayes GR, and Abaris ??. (2005) Evaluating Automated Capture Applied to Structured Autism Interventions. In Proceedings of Ubicom 2005: The 7th International Conference on Ubiquitous Computing, September, Tokyo, Japan, 2005.
Liu WS, Pappas GD, and Carter CS. (2005) Oxytocin receptors are reduced in cortical regions in haploinsufficient (+/-) mice. Neurological Research, 27:339-345.
McVicar KA, Ballaban-Gil K, Rapin I, Moshe SL and Shinnar S. (2005) Epileptiform EEG abnormalities in children with language regression. Neurology, 65(1):129-31.
Ming X, Julu P, Brimacombe M, Connor S, and Daniels M. (2005) Reduced cardiac parasympathetic activity in children with autism. Brain Dev., 27(7):509-16.
Ming X, Stein TP, Brimacombe M, Johnson WG, Lambert GH, and Wagner GC. (2005) Increased excretion of a lipid peroxidation biomarker in autism. Prostaglandins Leukot Essent Fatty Acids, 73(5):379-84.
Molloy CA, Keddache M, Martin LJ. (2005) Evidence for linkage on 21q and 7q in a subset of autism characterized by developmental regression. Mol Psychiatry, 10(8):741-6.
Moretti P, Bouwknecht JA, Teague R, Paylor R, Zoghbi HY. (2005) Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet., 14(2):205-20.
Murcia CL, Gulden F, and Herrup K. (2005) A question of balance: a proposal for new mouse models of autism. Int. J. Devl Neuroscience, Vol. 23:265-275.
Nayate A, Bradshaw JL, and Rinehart NJ. (2005) Autism and Asperger’s disorder: are they movement disorders involving the cerebellum and/or basal ganglia? Brain Res Bull, 67(4):327-34.
Nowinski CV, Minshew NJ, Luna B, Takarae Y, and Sweeney JA. (2005) Oculomotor studies of cerebellar function in autism. Psychiatry Research, Vol.137:11-19.
Palmen SJ, van Engeland H, Hof PR, and Schmitz C. (2005) Neuropathological findings in autism. Brain, 127:2572-83.
Pardo CA, Vargas DL, and Zimmerman AW. (2005) Immunity, neuroglia and neuroinflammation in autism. Int Rev Psychiatry. 17(6):485-95.
Percaccio CR, Engineer ND, Pruette AL, Pandya PK, Moucha R, Rathbun DL, and Kilgard MP. (2005) Environmental enrichment increases paired-pulse depression in rat auditory cortex. J Neurophysiol, 94(5):3590-600.
Pickett JP and London E. (2005) The neuropathology of autism: a review. Journal of Neuropathology and Experimental Neurology, 64(11): 925-935.
Prasad HC, Zhu CB, McCauley JL, Samuvel DJ, Ramamoorthy S, Shelton RC, Hewlett WA, Sutcliffe JS, and Blakely RD. (2005) Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase. Proc Natl Acad Sci U S A, 102(32):11545-50.
Ray MA, Graham AJ, Lee M, Perry RH, Court JA, and Perry EK. (2005) Neuronal nicotinic acetylcholine receptor subunits in autism: an immunohistochemical investigation in the thalamus. Neurobiol Dis, 19(3):366-77.
Rosso SB, Sussman D, Wynshaw-Boris A, and Salinas PC. (2005) Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci, 8(1):34-42.
Sandberg EM, Ma X, He K, Frank SJ, Ostrov DA, and Sayeski PP. (2005) Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation]. J Med Chem, 48(7):2526-33.
Schmitz C, van Kooten IA, Hof PR, van Engeland H, Patterson PH, and Steinbusch HW. (2005) Autism: neuropathology, alterations of the GABAergic system, and animal models. Int Rev Neurobiol, 71:1-26.
Shi L, Tu N, and Patterson PH. (2005) Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus. Int J Dev Neurosci, 23(2-3):299-305.
Shu W, Cho JY, Jiang Y, Zhang M, Weisz D, Elder GA, Schmeidler J, De Gasperi R, Sosa MA, Rabidou D, Santucci AC, Perl D, Morrisey E, and Buxbaum JD. Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene. Proc Natl Acad Sci USA, 102(27):9643-8. Epub 2005 Jun 27.
Shumyatsky GP, Malleret G, Shin RM, Takizawa S, Tully K, Tsvetkov E, Zakharenko SS, Joseph J, Vronskaya S, Yin D, Schubart UK, Kandel ER, and Bolshakov VY. (2005) Stathmin, a gene enriched in the amygdala, controls both learned and innate fear. Cell, 123(4):697-709.
Silbergeld EK, Silva IA, and Nyland JF. (2005) Mercury and autoimmunity: implications for occupational and environmental health. Toxicol Appl Pharmacol, 207(2 Suppl):282-92.
Silk T, Vance A, Rinehart N, Egan G, O’Boyle M, Bradshaw JL, and Cunnington R. (2005) Fronto-parietal activation in attention-deficit hyperactivity disorder, combined type: functional magnetic resonance imaging study. Br J Psychiatry, 187:282-3.
Silva IA, El Nabawi M, Hoover D, and Silbergeld EK. (2005) Prenatal HgCl2 exposure in BALB/c mice: gender-specific effects on the ontogeny of the immune system. Dev Comp Immunol, 29(2):171-83.
Silva IA, Graber J, Nyland JF, and Silbergeld EK. (2005) In vitro HgCl2 exposure of immune cells at different stages of maturation: effects on phenotype and function. Environ Res, 98(3):341-8.
Stachiowiak B, Harvey C, Menon SD, Mensah AK, Mnatzakanian N, Alfred SE, Guo R, Scherer SW, Kennedy JL, Roberts W, Minassian BA, Srivistava AK, and Vincent JB. Mutation analysis of the Rett syndrome gene (MCEP2) exon 1 in autism and mental retardation, and genetic studies of the distal portion of chromosome Xq. Am J Med Genet Part B (Neuropsychiatric Genetics), 138B: 70-71.
Stone V. (2005) Theory of Mind and the Evolution of Social Intelligence , In “Social Neuroscience: People Thinking About People.” J. Cacciopo, (Ed.), (Mass: MIT Press).
Strata F, Deipolyi AR, Bonham BH, Chang EF, Liu RC, Nakahara H, and Merzenich MM. (2005) Perinatal anoxia degrades auditory system function in rats. Proc Natl Acad Sci USA, 102(52):19156-61.
Sutcliffe JS, Delahanty RJ, Prasad HC, McCauley JL, Han Q, Jiang L, Li C, Folstein SE, and Blakely RD. (2005) Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors. Am J Hum Genet, (2):265-79.
Theoret H and Fecteau S. (2005) Making the case for mirror neuron system involvement in language development: what about autism and blindness? Behavioral and Brain Sciences, 28: 145-146.
Theoret H, Halligan E, Kobayashi M, Fregni F, Tager-Flusberg H, and Pascual-Leone, A. (2005) Impaired motor facilitation during action observation in individuals with autism spectrum disorder. Current Biology, 15: 84-85.
Welsh JP, Ahn ES, and Placantonakis DG. (2005) Is autism due to brain desynchronization? International Journal of Developmental Neuroscience, 23:253-263.
Xie Z, Hugan RL, and Penzes P. (2005) Activity-Dependent Dendritic Spine Structural Plasticity Is Regulated by Small GTPase Rap1 and Its Target AF-6. Neuron, 48: 605–618.
Yel L, Brown LE, Su K, Gollapudi S, and Gupta S. (2005) Thimerosal induces neuronal cell apoptosis by causing cytochrome c and apoptosis-inducing factor release from mitochondria. Int J Mol Med, 16(6):971-7.
Ylisaukko-oja T, Rehnstrom K, Auranen M, Vanhala R, Alen R, Kempas E, Ellonen P, Turunen JA, Makkonen I, Riikonen R, Nieminen-von Wendt T, von Wendt L, Peltonen L, and Jarvela I. (2005) Analysis of four neuroligin genes as candidates for autism. Eur J Hum Gen, 13(12):1285-92.
Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, and Zoghbi HY. (2005) Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proc Natl Acad Sci USA. 102(49):17551-8. Epub 2005 Oct 26.
Zwaigenbaum L, Bryson S , Rogers T, Roberts W, Brian J, and Szatmari P. (2005) Behavioral manifestations of autism in the first year of life. Int. J. Devl Neuroscience, 23:143–152.
Autistic people have fought the inclusion of ABA in therapy for us since before Autism Speaks, and other non-Autistic-led autism organizations, started lobbying legislation to get it covered by insurances and Medicaid.
ABA is a myth originally sold to parents that it would keep their Autistic child out of an institution. Today, parents are told that with early intervention therapy their child will either be less Autistic or no longer Autistic by elementary school, and can be mainstreamed in typical education classes. ABA is very expensive to pay out of pocket. Essentially, Autism Speaks has justified the big price tag up front will offset the overall burden on resources for an Autistic’s lifetime. The recommendation for this therapy is 40 hours a week for children and toddlers.
The original study that showed the success rate of ABA to be at 50% has never been replicated. In fact, the study of ABA by United States Department of Defense was denounced as a failure. Not just once, but multiple times. Simply stated: ABA doesn’t work. In study after repeated study: ABA (conversion therapy) doesn’t work.
What more recent studies do show: Autistics who experienced ABA therapy are at high risk to develop PTSD and other lifelong trauma-related conditions. Historically, the autism organizations promoting ABA as a cure or solution have silenced Autistic advocates’ opposition. ABA is also known as gay conversion therapy.
The ‘cure’ for Autistics not born yet is the prevention of birth.
The ‘cure’ is a choice to terminate a pregnancy based on ‘autism risk.’ The cure is abortion. This is the same ‘cure’ society has for Down Syndrome.
This is eugenics 2021. Instead of killing Autistics and disabled children in gas chambers or ‘mercy killings’ like in Aktion T4, it’ll happen at the doctor’s office, quietly, one Autistic baby at a time. Different approaches yes, but still eugenics and the extinction of an entire minority group of people.
Fact: You can’t cure Autistics from being Autistic.
Fact: You can’t recover an Autistic from being Autistic.
Fact: You can groom an Autistic to mask and hide their traits. Somewhat. … however, this comes at the expense of the Autistic child, promotes Autistic Burnout (this should not be confused with typical burnout, Autistic Burnout can kill Autistics), and places the Autistic child at high risk for PTSD and other lifelong trauma-related conditions.
[Note: Autism is NOT a disease, but a neurodevelopmental difference and disability.]
Fact: Vaccines Do Not Cause Autism.