Archived | AGRE: About the Rutgers University Cell and DNA Repository | Circa April 2001 #AutisticHistory #NotAnAutisticAlly

About the Rutgers University Cell and DNA Repository 
by Jay A. Tischfield, Ph.D. 

Many scientists now believe that autism is a complex oligogenic disorder. They propose that autism is the result of the interaction of several inherited factors (genes) and unknown environmental influences. Identifying genes responsible for autism is likely to yield insight into this condition and shed light on new avenues for therapy. A basic approach toward identifying such genes involves the study of families with one or more autistic individuals. The study rationale is simple in principle but very complex in application. The underlying principle is that affected individuals within a family will be more likely to share certain genes that confer liability to autism. Conversely, it is less likely that affected and unaffected individuals in a particular family will share these genes. Thus, the quest is to identify genes that are common to affected individuals but less common among the unaffected.

The Rutgers University Cell and DNA Repository (RUCDR) plays a key role in this multinational quest for genes responsible for autism and several other complex diseases such as schizophrenia, bipolar disorder, Alzheimer disease, hypertension, certain cancers, alcoholism and other conditions involving substance abuse. After a potentially informative family is identified, blood is drawn and shipped overnight to RUCDR.

Upon receipt of the anonymous (e.g., personal identifiers removed) blood, the white cells are separated from the whole blood, removed and treated with Epstein Barr virus, a fairly common virus known to cause mononucleosis. In over 95% of the cases, the virus will “transform” the white cells such that they will begin to divide at a rapid rate for an indefinite period.

This allows the RUCDR staff to grow large numbers of these transformed cells, typically over a billion for each subject, such that a substantial amount (one-thousandth of a gram, for example) of their DNA, the material that contains the genes, can be extracted and stored. Once the DNA is available, the transformed cells are cryopreserved and stored in a state of “suspended animation” in large tanks containing liquid nitrogen. These cells are completely viable and can be “defrosted” to yield live cultures should more DNA be required or should studies with living cells be desired.

Thus, the RUCDR can supply DNA and cells to qualified researchers throughout the world. A major advantage of this approach is that all of the scientists will be able to study the same families and the supply of DNA and cells is virtually inexhaustible. DNA is usually supplied to “genotyping” laboratories that determine which genetic markers are present in each individual.

The RUCDR works with over 40 schools of medicine in the United States as well as more than six foreign organizations in China, Taiwan, Daghestan, Africa and elsewhere. They may test for as many as one thousand genetic markers and all data are entered into computer databases, which are then analyzed by a mathematically oriented group known as “statistical geneticists.” These individuals point out regions on chromosomes that might contain susceptibility genes. Molecular geneticists then intensely dissect these regions in an effort to identify genes important in autism. 

While the entire process of finding genes may take many years, it has been dramatically successful with many of the simpler genetic diseases. The RUCDR is one of the largest and most advanced of its kind, having developed several innovative procedures in this field. The professional staff is dedicated to helping individual researchers attain their goals by providing customized services and consultation.

The RUCDR repository has experienced scientific staff and board certified Medical Geneticists. All understand the sacrifices of study subjects as well as the needs of the participating families and are dedicated to the common goal of eradicating these diseases by understanding their genetic bases.


More With AGRE



Note/Warning:

Autistic people have fought the inclusion of ABA in therapy for us since before Autism Speaks, and other non-Autistic-led autism organizations, started lobbying legislation to get it covered by insurances and Medicaid. 

ABA is a myth originally sold to parents that it would keep their Autistic child out of an institution. Today, parents are told that with early intervention therapy their child will either be less Autistic or no longer Autistic by elementary school, and can be mainstreamed in typical education classes. ABA is very expensive to pay out of pocket. Essentially, Autism Speaks has justified the big price tag up front will offset the overall burden on resources for an Autistic’s lifetime. The recommendation for this therapy is 40 hours a week for children and toddlers.

The original study that showed the success rate of ABA to be at 50% has never been replicated. In fact, the study of ABA by United States Department of Defense was denounced as a failure. Not just once, but multiple times. Simply stated: ABA doesn’t workIn study after repeated study: ABA (conversion therapy) doesn’t work. 

What more recent studies do show: Autistics who experienced ABA therapy are at high risk to develop PTSD and other lifelong trauma-related conditions. Historically, the autism organizations promoting ABA as a cure or solution have silenced Autistic advocates’ opposition. ABA is also known as gay conversion therapy.


The ‘cure’ for Autistics not born yet is the prevention of birth. 

The ‘cure’ is a choice to terminate a pregnancy based on ‘autism risk.’ The cure is abortion. This is the same ‘cure’ society has for Down Syndrome. 

This is eugenics 2021. Instead of killing Autistics and disabled children in gas chambers or ‘mercy killings’ like in Aktion T4, it’ll happen at the doctor’s office, quietly, one Autistic baby at a time. Different approaches yes, but still eugenics and the extinction of an entire minority group of people.


Fact: You can’t cure Autistics from being Autistic.

Fact: You can’t recover an Autistic from being Autistic.

Fact: You can groom an Autistic to mask and hide their traits. Somewhat. … however, this comes at the expense of the Autistic child, promotes Autistic Burnout (this should not be confused with typical burnout, Autistic Burnout can kill Autistics), and places the Autistic child at high risk for PTSD and other lifelong trauma-related conditions.


[Note: Autism is NOT a disease, but a neurodevelopmental difference and disability.]


Fact: Vaccines Do Not Cause Autism.


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