Archived | Gene mutation contributes to autism | Circa April 6, 2012 #NotAnAutisticAlly


Gene mutation contributes to autism

LOS ANGELES, April 6 (UPI) — U.S. researchers estimate there are likely about 1,000 or more genes that contribute to autism spectrum disorder risk, but mutations might be the key.

Dr. Daniel Geschwind, a professor of neurology and psychiatry at the University of California, Los Angeles, and colleagues from Yale University, Carnegie Mellon University and the University of Pittsburgh, completed “whole-exome sequencing” of 238 parent-child quartets.

A quartet is defined as two parents and one child without autism spectrum disorder and one child with autism spectrum disorder. Whole-exome sequencing is an efficient strategy to sequence the coding regions of the genome selectively, as a cheaper but still effective alternative to whole genome sequencing.

The researchers compared mutation rates between unaffected individuals and those with autism spectrum disorder within a family, and then compared autism spectrum disorder mutations to the entire study.

They found multiple variations between unaffected and affected groups. Specifically, among a total of 279 coding mutations, they identified a single instance in individual children with autism spectrum disorder — and not in siblings — in which two independent mutations disrupt the gene SCN2A.

That same mutation was found in all the unrelated children with autism spectrum disorder, confirming its importance.

The study was published in the journal Nature.


More With Daniel Geschwind



Note/Warning:

Autistic people have fought the inclusion of ABA in therapy for us since before Autism Speaks, and other non-Autistic-led autism organizations, started lobbying legislation to get it covered by insurances and Medicaid. 

ABA is a myth originally sold to parents that it would keep their Autistic child out of an institution. Today, parents are told that with early intervention therapy their child will either be less Autistic or no longer Autistic by elementary school, and can be mainstreamed in typical education classes. ABA is very expensive to pay out of pocket. Essentially, Autism Speaks has justified the big price tag up front will offset the overall burden on resources for an Autistic’s lifetime. The recommendation for this therapy is 40 hours a week for children and toddlers.

The original study that showed the success rate of ABA to be at 50% has never been replicated. In fact, the study of ABA by United States Department of Defense was denounced as a failure. Not just once, but multiple times. Simply stated: ABA doesn’t workIn study after repeated study: ABA (conversion therapy) doesn’t work. 

What more recent studies do show: Autistics who experienced ABA therapy are at high risk to develop PTSD and other lifelong trauma-related conditions. Historically, the autism organizations promoting ABA as a cure or solution have silenced Autistic advocates’ opposition. ABA is also known as gay conversion therapy.


The ‘cure’ for Autistics not born yet is the prevention of birth. 

The ‘cure’ is a choice to terminate a pregnancy based on ‘autism risk.’ The cure is abortion. This is the same ‘cure’ society has for Down Syndrome. 

This is eugenics 2021. Instead of killing Autistics and disabled children in gas chambers or ‘mercy killings’ like in Aktion T4, it’ll happen at the doctor’s office, quietly, one Autistic baby at a time. Different approaches yes, but still eugenics and the extinction of an entire minority group of people.


Fact: You can’t cure Autistics from being Autistic.

Fact: You can’t recover an Autistic from being Autistic.

Fact: You can groom an Autistic to mask and hide their traits. Somewhat. … however, this comes at the expense of the Autistic child, promotes Autistic Burnout (this should not be confused with typical burnout, Autistic Burnout can kill Autistics), and places the Autistic child at high risk for PTSD and other lifelong trauma-related conditions.


[Note: Autism is NOT a disease, but a neurodevelopmental difference and disability.]


Fact: Vaccines Do Not Cause Autism.


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